G62S (p.Gly62Ser) variant of VKORC1 (Q9BQB6)
G62S (p.Gly62Ser) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
G62S (p.Gly62Ser) variant details
- p.Gly62Ser
- gnomAD rs1158890375
- Missense
- Variant Prioritization Score for Impact Estimate 0.775
- REVEL 0.77
- CADD 26.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available