G2D (p.Gly2Asp) variant of VKORC1 (Q9BQB6)
G2D (p.Gly2Asp) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
G2D (p.Gly2Asp) variant details
- p.Gly2Asp
- ExAC rs757332613
- gnomAD rs757332613
- Missense
- Variant Prioritization Score for Impact Estimate 0.525
- REVEL 0.55
- CADD 22.90
- PolyPhen-2 0.57
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available