G19S (p.Gly19Ser) variant of VKORC1 (Q9BQB6)
G19S (p.Gly19Ser) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
G19S (p.Gly19Ser) variant details
- p.Gly19Ser
- gnomAD rs1163079898
- Missense
- Variant Prioritization Score for Impact Estimate 0.768
- REVEL 0.77
- CADD 24.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available