F83C (p.Phe83Cys) variant of VKORC1 (Q9BQB6)
F83C (p.Phe83Cys) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
F83C (p.Phe83Cys) variant details
- p.Phe83Cys
- Ensembl rs1057109736
- Missense
- Variant Prioritization Score for Impact Estimate 0.644
- REVEL 0.82
- CADD 26.70
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available