A34S (p.Ala34Ser) variant of VKORC1 (Q9BQB6)
A34S (p.Ala34Ser) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
A34S (p.Ala34Ser) variant details
- p.Ala34Ser
- TOPMed rs887072982
- gnomAD rs887072982
- Missense
- Variant Prioritization Score for Impact Estimate 0.539
- REVEL 0.49
- CADD 23.90
- PolyPhen-2 0.92
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available