A34P (p.Ala34Pro) variant of VKORC1 (Q9BQB6)
A34P (p.Ala34Pro) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
A34P (p.Ala34Pro) variant details
- p.Ala34Pro
- TOPMed rs887072982
- gnomAD rs887072982
- Missense
- Variant Prioritization Score for Impact Estimate 0.655
- REVEL 0.68
- CADD 26.80
- PolyPhen-2 0.99
- SIFT 0.14
- Most common in the 1KG:GIH population (allele frequency 0.0053)
- Structural context available