A26S (p.Ala26Ser) variant of VKORC1 (Q9BQB6)
A26S (p.Ala26Ser) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
A26S (p.Ala26Ser) variant details
- p.Ala26Ser
- ExAC rs770703948
- gnomAD rs770703948
- Missense
- Variant Prioritization Score for Impact Estimate 0.498
- REVEL 0.53
- CADD 21.70
- PolyPhen-2 0.06
- SIFT 0.07
- Most common in the Ashkenazi Jewish population (allele frequency 5.1e-05)
- Structural context available