Y53H (p.Tyr53His) variant of VIM (Vimentin)
Y53H (p.Tyr53His) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
Y53H (p.Tyr53His) variant details
- p.Tyr53His
- gnomAD 10-17229579-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.401
- REVEL 0.36
- MetaLR 0.61
- MetaSVM 0.13
- CADD 25.40
- PolyPhen-2 0.79
- SIFT 0.45
- Population evidence available
- Structural context available
- Literature evidence available