S5T (p.Ser5Thr) variant of VIM (Vimentin)
S5T (p.Ser5Thr) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
S5T (p.Ser5Thr) variant details
- p.Ser5Thr
- gnomAD 10-17229435-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.18
- MetaLR 0.27
- MetaSVM -0.89
- CADD 21.80
- PolyPhen-2 0.00
- SIFT 0.91
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available