S49T (p.Ser49Thr) variant of VIM (Vimentin)
S49T (p.Ser49Thr) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
S49T (p.Ser49Thr) variant details
- p.Ser49Thr
- gnomAD 10-17229568-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.248
- REVEL 0.13
- MetaLR 0.46
- MetaSVM -0.39
- CADD 22.00
- PolyPhen-2 0.01
- SIFT 0.37
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available