S49G (p.Ser49Gly) variant of VIM (Vimentin)
S49G (p.Ser49Gly) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
S49G (p.Ser49Gly) variant details
- p.Ser49Gly
- ExAC rs769749512
- gnomAD rs769749512
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.20
- CADD 21.80
- PolyPhen-2 0.01
- SIFT 0.25
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available