S2P (p.Ser2Pro) variant of VIM (Vimentin)
S2P (p.Ser2Pro) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
S2P (p.Ser2Pro) variant details
- p.Ser2Pro
- ExAC rs756656437
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.33
- CADD 22.80
- PolyPhen-2 0.04
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available