S27R (p.Ser27Arg) variant of VIM (Vimentin)
S27R (p.Ser27Arg) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
S27R (p.Ser27Arg) variant details
- p.Ser27Arg
- cosmic curated COSV56406
- ExAC rs775343323
- TOPMed rs775343323
- gnomAD rs775343323
- Missense
- Variant Prioritization Score for Impact Estimate 0.281
- REVEL 0.24
- CADD 22.10
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available