S26C (p.Ser26Cys) variant of VIM (Vimentin)
S26C (p.Ser26Cys) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
S26C (p.Ser26Cys) variant details
- p.Ser26Cys
- Ensembl rs1846740611
- Missense
- Variant Prioritization Score for Impact Estimate 0.441
- REVEL 0.38
- CADD 24.10
- PolyPhen-2 0.67
- SIFT 0.17
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available