S10Y (p.Ser10Tyr) variant of VIM (Vimentin)
S10Y (p.Ser10Tyr) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data, published literature, and structural context.
S10Y (p.Ser10Tyr) variant details
- p.Ser10Tyr
- gnomAD 10-17229451-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.807
- REVEL 0.80
- MetaLR 0.84
- MetaSVM 0.89
- CADD 29.00
- PolyPhen-2 0.99
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available