R4S (p.Arg4Ser) variant of VIM (Vimentin)
R4S (p.Arg4Ser) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
R4S (p.Arg4Ser) variant details
- p.Arg4Ser
- gnomAD 10-17229434-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.398
- REVEL 0.19
- MetaLR 0.25
- MetaSVM -0.87
- CADD 21.70
- PolyPhen-2 0.00
- SIFT 0.69
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available