R45C (p.Arg45Cys) variant of VIM (Vimentin)
R45C (p.Arg45Cys) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.
R45C (p.Arg45Cys) variant details
- p.Arg45Cys
- gnomAD 10-17229555-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.717
- REVEL 0.70
- MetaLR 0.68
- MetaSVM 0.34
- CADD 27.80
- PolyPhen-2 0.96
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available