R28W (p.Arg28Trp) variant of VIM (Vimentin)
R28W (p.Arg28Trp) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
R28W (p.Arg28Trp) variant details
- p.Arg28Trp
- cosmic curated COSV10730
- TOPMed rs1194887764
- gnomAD rs1194887764
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- REVEL 0.32
- CADD 23.90
- PolyPhen-2 0.74
- SIFT 0.10
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available