R23W (p.Arg23Trp) variant of VIM (Vimentin)
R23W (p.Arg23Trp) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
R23W (p.Arg23Trp) variant details
- p.Arg23Trp
- TOPMed rs910563895
- Missense
- Variant Prioritization Score for Impact Estimate 0.622
- REVEL 0.71
- CADD 26.50
- PolyPhen-2 0.82
- SIFT 0.18
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available