R12S (p.Arg12Ser) variant of VIM (Vimentin)
R12S (p.Arg12Ser) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
R12S (p.Arg12Ser) variant details
- p.Arg12Ser
- gnomAD rs1220895620
- Missense
- Variant Prioritization Score for Impact Estimate 0.488
- REVEL 0.54
- CADD 24.30
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available