P18L (p.Pro18Leu) variant of VIM (Vimentin)
P18L (p.Pro18Leu) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
P18L (p.Pro18Leu) variant details
- p.Pro18Leu
- cosmic curated COSV56407
- TOPMed rs11545549
- gnomAD rs11545549
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.20
- CADD 18.80
- PolyPhen-2 0.00
- SIFT 0.09
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available