L52I (p.Leu52Ile) variant of VIM (Vimentin)
L52I (p.Leu52Ile) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
L52I (p.Leu52Ile) variant details
- p.Leu52Ile
- Ensembl rs1588731496
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.07
- CADD 19.30
- PolyPhen-2 0.03
- SIFT 0.41
- Most common in the Middle Eastern population (allele frequency 0.0011)
- Structural context available