L40P (p.Leu40Pro) variant of VIM (Vimentin)
L40P (p.Leu40Pro) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
L40P (p.Leu40Pro) variant details
- p.Leu40Pro
- gnomAD 10-17229541-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.541
- REVEL 0.56
- MetaLR 0.43
- MetaSVM -0.37
- CADD 24.10
- PolyPhen-2 0.00
- SIFT 0.24
- Population evidence available
- Structural context available
- Literature evidence available