A21S (p.Ala21Ser) variant of VIM (Vimentin)
A21S (p.Ala21Ser) in VIM (Vimentin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
A21S (p.Ala21Ser) variant details
- p.Ala21Ser
- gnomAD 10-17229483-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.16
- MetaLR 0.22
- MetaSVM -0.89
- CADD 16.40
- PolyPhen-2 0.01
- SIFT 0.78
- Population evidence available
- Structural context available
- Literature evidence available