V181L (p.Val181Leu) variant of VCP (P55072)
V181L (p.Val181Leu) in VCP (P55072) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
V181L (p.Val181Leu) variant details
- p.Val181Leu
- gnomAD rs1275676999
- Missense
- Variant Prioritization Score for Impact Estimate 0.543
- REVEL 0.41
- CADD 22.10
- PolyPhen-2 0.02
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available