T127A (p.Thr127Ala) variant of VCP (P55072)
T127A (p.Thr127Ala) in VCP (P55072) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
T127A (p.Thr127Ala) variant details
- p.Thr127Ala
- gnomAD rs1287162663
- Missense
- Variant Prioritization Score for Impact Estimate 0.601
- REVEL 0.65
- AlphaMissense 0.17
- MetaLR 0.73
- MetaSVM 0.27
- CADD 22.70
- PolyPhen-2 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available