P188S (p.Pro188Ser) variant of VCP (P55072)
P188S (p.Pro188Ser) in VCP (P55072) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
P188S (p.Pro188Ser) variant details
- p.Pro188Ser
- gnomAD rs1309590903
- Missense
- Variant Prioritization Score for Impact Estimate 0.782
- REVEL 0.77
- CADD 28.10
- PolyPhen-2 0.81
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available