K190R (p.Lys190Arg) variant of VCP (P55072)
K190R (p.Lys190Arg) in VCP (P55072) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
K190R (p.Lys190Arg) variant details
- p.Lys190Arg
- ExAC rs776154559
- TOPMed rs776154559
- gnomAD rs776154559
- Missense
- Variant Prioritization Score for Impact Estimate 0.433
- REVEL 0.32
- CADD 22.90
- PolyPhen-2 0.01
- SIFT 0.20
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available