C77G (p.Cys77Gly) variant of VCP (P55072)
C77G (p.Cys77Gly) in VCP (P55072) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
C77G (p.Cys77Gly) variant details
- p.Cys77Gly
- ExAC rs781182130
- gnomAD rs781182130
- Missense
- Variant Prioritization Score for Impact Estimate 0.729
- REVEL 0.80
- CADD 24.70
- PolyPhen-2 0.74
- SIFT 0.30
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available