T81P (p.Thr81Pro) variant of VCAN (Versican core protein)
T81P (p.Thr81Pro) in VCAN (Versican core protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
T81P (p.Thr81Pro) variant details
- p.Thr81Pro
- gnomAD 5-83490268-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.454
- REVEL 0.39
- CADD 25.40
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available
- Literature evidence available