T18S (p.Thr18Ser) variant of VCAN (Versican core protein)
T18S (p.Thr18Ser) in VCAN (Versican core protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
T18S (p.Thr18Ser) variant details
- p.Thr18Ser
- gnomAD 5-83483570-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.09
- CADD 18.70
- PolyPhen-2 0.15
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available
- Literature evidence available