T18A (p.Thr18Ala) variant of VCAN (Versican core protein)
T18A (p.Thr18Ala) in VCAN (Versican core protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
T18A (p.Thr18Ala) variant details
- p.Thr18Ala
- ExAC rs751482841
- gnomAD rs751482841
- Missense
- Variant Prioritization Score for Impact Estimate 0.148
- REVEL 0.07
- CADD 15.70
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available