T14I (p.Thr14Ile) variant of VCAN (Versican core protein)
T14I (p.Thr14Ile) in VCAN (Versican core protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
T14I (p.Thr14Ile) variant details
- p.Thr14Ile
- gnomAD rs1304018175
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.06
- CADD 21.50
- PolyPhen-2 0.03
- SIFT 0.04
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available