S59R (p.Ser59Arg) variant of VCAN (Versican core protein)
S59R (p.Ser59Arg) in VCAN (Versican core protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
S59R (p.Ser59Arg) variant details
- p.Ser59Arg
- ExAC rs775793051
- gnomAD rs775793051
- Missense
- Variant Prioritization Score for Impact Estimate 0.147
- REVEL 0.13
- CADD 13.60
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available