S35C (p.Ser35Cys) variant of VCAN (Versican core protein)
S35C (p.Ser35Cys) in VCAN (Versican core protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
S35C (p.Ser35Cys) variant details
- p.Ser35Cys
- gnomAD 5-83490131-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.413
- REVEL 0.45
- CADD 22.70
- PolyPhen-2 0.98
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available