R33K (p.Arg33Lys) variant of VCAN (Versican core protein)
R33K (p.Arg33Lys) in VCAN (Versican core protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
R33K (p.Arg33Lys) variant details
- p.Arg33Lys
- gnomAD 5-83490125-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.107
- REVEL 0.06
- CADD 4.80
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available
- Literature evidence available