P31S (p.Pro31Ser) variant of VCAN (Versican core protein)
P31S (p.Pro31Ser) in VCAN (Versican core protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
P31S (p.Pro31Ser) variant details
- p.Pro31Ser
- gnomAD 5-83490118-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0707
- REVEL 0.03
- CADD 1.25
- PolyPhen-2 0.21
- SIFT 0.07
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available
- Literature evidence available