L36V (p.Leu36Val) variant of VCAN (Versican core protein)
L36V (p.Leu36Val) in VCAN (Versican core protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
L36V (p.Leu36Val) variant details
- p.Leu36Val
- ExAC rs777022702
- TOPMed rs777022702
- gnomAD rs777022702
- Missense
- Variant Prioritization Score for Impact Estimate 0.424
- REVEL 0.30
- CADD 23.60
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available