K73E (p.Lys73Glu) variant of VCAN (Versican core protein)
K73E (p.Lys73Glu) in VCAN (Versican core protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
K73E (p.Lys73Glu) variant details
- p.Lys73Glu
- gnomAD 5-83490244-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.23
- CADD 25.70
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available
- Literature evidence available