I16T (p.Ile16Thr) variant of VCAN (Versican core protein)
I16T (p.Ile16Thr) in VCAN (Versican core protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
I16T (p.Ile16Thr) variant details
- p.Ile16Thr
- gnomAD rs1367479916
- Missense
- Variant Prioritization Score for Impact Estimate 0.245
- REVEL 0.10
- CADD 22.90
- PolyPhen-2 0.07
- SIFT 0.01
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available