F61C (p.Phe61Cys) variant of VCAN (Versican core protein)
F61C (p.Phe61Cys) in VCAN (Versican core protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
F61C (p.Phe61Cys) variant details
- p.Phe61Cys
- gnomAD 5-83490209-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.40
- CADD 24.90
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available
- Literature evidence available