Y8C (p.Tyr8Cys) variant of UNG (Uracil-DNA glycosylase)
Y8C (p.Tyr8Cys) in UNG (Uracil-DNA glycosylase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
Y8C (p.Tyr8Cys) variant details
- p.Tyr8Cys
- TOPMed rs1215646041
- gnomAD rs1215646041
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.25
- CADD 24.00
- PolyPhen-2 0.32
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available