V33L (p.Val33Leu) variant of UNG (Uracil-DNA glycosylase)
V33L (p.Val33Leu) in UNG (Uracil-DNA glycosylase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
V33L (p.Val33Leu) variant details
- p.Val33Leu
- gnomAD 12-109097776-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.194
- REVEL 0.04
- CADD 15.80
- PolyPhen-2 0.00
- SIFT 0.34
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available