T6R (p.Thr6Arg) variant of UNG (Uracil-DNA glycosylase)
T6R (p.Thr6Arg) in UNG (Uracil-DNA glycosylase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
T6R (p.Thr6Arg) variant details
- p.Thr6Arg
- TOPMed rs990883898
- gnomAD rs990883898
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.23
- CADD 22.90
- PolyPhen-2 0.37
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available