T6M (p.Thr6Met) variant of UNG (Uracil-DNA glycosylase)
T6M (p.Thr6Met) in UNG (Uracil-DNA glycosylase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
T6M (p.Thr6Met) variant details
- p.Thr6Met
- TOPMed rs990883898
- gnomAD rs990883898
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.17
- CADD 26.80
- PolyPhen-2 0.73
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available