P24H (p.Pro24His) variant of UNG (Uracil-DNA glycosylase)
P24H (p.Pro24His) in UNG (Uracil-DNA glycosylase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
P24H (p.Pro24His) variant details
- p.Pro24His
- gnomAD 12-109097750-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.305
- REVEL 0.07
- CADD 22.70
- PolyPhen-2 0.22
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.6e-05)
- Structural context available
- Literature evidence available