P13H (p.Pro13His) variant of UNG (Uracil-DNA glycosylase)
P13H (p.Pro13His) in UNG (Uracil-DNA glycosylase) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
P13H (p.Pro13His) variant details
- p.Pro13His
- NCI-TCGA Cosmic COSV9965
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.13
- CADD 23.60
- PolyPhen-2 0.56
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available