K18R (p.Lys18Arg) variant of UNG (Uracil-DNA glycosylase)
K18R (p.Lys18Arg) in UNG (Uracil-DNA glycosylase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
K18R (p.Lys18Arg) variant details
- p.Lys18Arg
- gnomAD rs1358864015
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.08
- CADD 20.40
- PolyPhen-2 0.40
- SIFT 0.29
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available