G3S (p.Gly3Ser) variant of UNG (Uracil-DNA glycosylase)
G3S (p.Gly3Ser) in UNG (Uracil-DNA glycosylase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
G3S (p.Gly3Ser) variant details
- p.Gly3Ser
- ExAC rs781643146
- gnomAD rs781643146
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- REVEL 0.19
- CADD 24.20
- PolyPhen-2 0.42
- SIFT 0.09
- Most common in the Ashkenazi Jewish population (allele frequency 3.9e-05)
- Structural context available