G3C (p.Gly3Cys) variant of UNG (Uracil-DNA glycosylase)
G3C (p.Gly3Cys) in UNG (Uracil-DNA glycosylase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
G3C (p.Gly3Cys) variant details
- p.Gly3Cys
- gnomAD 12-109097686-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.601
- REVEL 0.51
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available